Never flush remedies down the bathroom or pour them into a drain Except if instructed to do so. Appropriately discard this products when it is actually expired or no more desired. Talk to your pharmacist or community waste disposal enterprise.

This isn't an entire list of feasible Unwanted effects. For those who notice other effects not shown above, contact your medical doctor or pharmacist.

Lengthy-time period usage of promethazine/codeine may possibly affect your ability to come to be pregnant or receive a spouse Expecting. Chat with your Health care provider When you've got any fears.

Any time you take codeine, your liver breaks it down into morphine. Then, it crosses into your brain and binds to opioid receptors. Opioid receptors can alter how you're feeling suffering and decrease the urge to cough.

Due to the fact 2019, there are already expanding experiences from the media of codeine linctus remaining misused as an ingredient in a recreational consume, normally often called ‘Purple Drank’.

Promethazine hydrochloride wasn't mutagenic inside the in vitro bacterial reverse mutation assay or clastogenic from the in vitro Chinese hamster ovary (CHO) cell check here chromosomal aberration assay.

When supplied concomitantly with promethazine, the dose of barbiturates needs to be lowered by not less than one particular-half, as well as the dose of narcotics ought to be lowered by website just one-quarter to 1-half. Dosage must be individualized. Abnormal quantities of promethazine HCl relative into a website narcotic may well produce restlessness and motor hyperactivity during the affected individual with agony; these signs ordinarily vanish with enough Charge of the ache.

The following adverse reactions happen to be recognized for the duration of clinical reports, while in the literature, or through submit-approval usage of codeine and/or promethazine.

This product may trigger really serious mental/temper modifications and very serious (hardly ever deadly) respiratory complications. This products may include codeine or dihydrocodeine. Codeine and dihydrocodeine are transformed into strong opioid medicine (morphine or dihydromorphine) in One's body.

Pregnancy. Promethazine/codeine may well trigger hurt to an unborn infant. Explain to your healthcare company if you are or strategy more info to become Expecting. Your Health care company will recommend you if you should acquire promethazine/codeine if you are pregnant or endeavoring to get Expecting.

The following laboratory checks can be affected in sufferers who're getting therapy with promethazine hydrochloride.

常見之不良反應有：瘙癢、噁心、嘔吐、昏睡、口乾、瞳孔縮小、姿態性低血壓（orthostatic hypotension）、小便不暢、便秘。

This is probably not an entire listing of medicines that may interact with promethazine/codeine. Often check with your Health care provider.

Postmarketing cases of respiratory despair, which include fatalities, click here are described with utilization of promethazine hydrochloride in pediatric individuals lower than two yrs of age. A wide array of bodyweight-primarily based doses of promethazine hydrochloride have resulted in respiratory despair in these clients.